Research Article
A Kinetic-Model-Based Approach to Identify Malfunctioning Components in Signal Transduction Pathways from Artificial Clinical Data
Table 9
Rank of the possibility of the reactions whose upregulation causes the abnormal profiles with different noise levels.
| Rank | 20% | 40% | 60% | 80% | Reaction index | | Reaction index | | Reaction index | | Reaction index | |
| 1 | 10 | 0.98 | 10 | 0.92 | 10 | 0.85 | 10 | 0.80 | 2 | 45 | 0.83 | 45 | 0.80 | 45 | 0.74 | 45 | 0.68 | 3 | 46 | 0.58 | 46 | 0.56 | 46 | 0.51 | 46 | 0.48 | 4 | 47 | 0.57 | 47 | 0.56 | 47 | 0.51 | 47 | 0.48 | 5 | 41 | 0.55 | 41 | 0.54 | 41 | 0.49 | 41 | 0.46 | 6 | 35 | 0.12 | 35 | 0.12 | 35 | 0.11 | 35 | 0.10 | 7 | 40 | 0.11 | 40 | 0.10 | 112 | 0.086 | 12 | 0.079 | 8 | 43 | 0.11 | 43 | 0.10 | 43 | 0.083 | 9 | 0.064 | 9 | 12 | 0.10 | 12 | 0.093 | 40 | 0.083 | 43 | 0.062 | 10 | 9 | 0.079 | 9 | 0.075 | 9 | 0.070 | 40 | 0.062 |
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