Research Article

A Kinetic-Model-Based Approach to Identify Malfunctioning Components in Signal Transduction Pathways from Artificial Clinical Data

Table 9

Rank of the possibility of the reactions whose upregulation causes the abnormal profiles with different noise levels.

Rank20%40%60%80%
Reaction index Reaction index Reaction index Reaction index

1100.98100.92100.85100.80
2450.83450.80450.74450.68
3460.58460.56460.51460.48
4470.57470.56470.51470.48
5410.55410.54410.49410.46
6350.12350.12350.11350.10
7400.11400.101120.086120.079
8430.11430.10430.08390.064
9120.10120.093400.083430.062
1090.07990.07590.070400.062