Genetic Polymorphisms of IL-17F and TRAF3IP2 Could Be Predictive Factors of the Long-Term Effect of Infliximab against Crohn’s Disease

Figure 1

Flowchart of study design. A total of 113 CD patients were enrolled in this study. Of these patients, at the end of the 10-week IFX treatment, 103 patients showed response to IFX, 8 patients indicated loss of response to IFX, and IFX treatments of 2 patients were stopped due to side reactions of IFX. After 1 year of IFX treatment, 89 of the 103 patients still showed response to IFX, but the other 14 patients showed loss of response to IFX. CD: Crohn’s disease; IFX: infliximab.