Assessing the Impact of Mechanical Damage on Full-Thickness Porcine and Human Skin Using an In Vitro Approach

Table 3

TEWL data (number of experimentations with mean and median) obtained with healthy human (IntactHSkin) and porcine (IntactPigS.) skins and human stretch marks biopsies (StretchM.HSkin).

Type of skins		Average rank	Median (TEWL) g/m²/h	Mean (TEWL) g/m²/h
Intact pig skin	154	166.68	6.60	6.70 ± 0.23
30-strip pig skin (pooled protocols 1-2)	27	302.01	25.70	25.58 ± 0.56
Brush gel pig skin	9	290.00	23.60	23.53 ± 0.87
Razor pig skin	6	340.50	35.35	33.96 ± 1.18
Microneedle pig skin	14	300.35	24.40	25.45 ± 0.77
Intact human skin	106	77.92	3.95	4.23 ± 0.28
30-strip human skin (pooled protocols 1-2)	17	306.29	26.90	26.34 ± 0.70
Brush gel human skin	5	319.10	29.50	28.78 ± 1.30
Razor human skin	8	328.68	30.08	30.82 ± 1.02
Microneedle human skin	79	312.83	30.00	27.67 ± 0.97