Analysis of Hereditary Elliptocytosis with Decreased Binding of Eosin-5-maleimide to Red Blood Cells

Table 1

List of HE Patients.

Case	Family	HE type	Membrane protein abnormality; (SDS-PAGE)	Spectrin; patient/control (%); (SDS-PAGE)	Protein 4.1; patient/control (%); (SDS-PAGE)	Band 3; patient/control (%); (SDS-PAGE)	Rod-shaped; RBC; (%)	Ovalocytic; RBC; (%)	MCF; (units)	Hb; (g/dL)	Haptoglobin; (mg/dL)	ID-Bil; (mg/dL)	Reticulo (/μL)	MCV; (fL)	MCHC; (%)
1	A-1	Spherocytic HE	Partial spectrin deficiency	85.8	103.2	106.7	31.8	64.2	32.4	4.7	2	1.3	12.3	74.3	36.2
2	A-2	Spherocytic HE	Partial spectrin deficiency	85.5	95.1	107.5	8.0	80.0	30.2	Not; tested	2	1.4	Not; tested	Not; tested	Not; tested
3	B	Common HE	Membrane protein abnormality not detected	93.3	99.4	102.4	6.4	73.8	29.2	12.2	<8	1.3	25.7	86.3	35.2
4	C	Common HE	Membrane protein abnormality not detected	103.7	92.3	99.7	25.6	70.9	35.7	11.8	<2	0.9	8.6	89.6	33.5
5	D-1	Common HE	Membrane protein abnormality not detected	90.4	101.2	103.3	7.2	84.6	37.3	12.3	4	0.9	10.5	81.5	34.5
6	D-2	Common HE	Membrane protein abnormality not detected	92.4	104.0	104.9	11.5	82.2	36.6	12.2	18	1.3	7.7	75.8	35.5
7	D-3	Common HE	Membrane protein abnormality not detected	90.3	102.8	102.8	3.0	65.8	38.7	13.6	44	0.3	4.5	88.2	34.3
8	E-1	Common HE	Partial P4.1 deficiency	94.8	76.5	100.0	21.6	70.6	37.2	12.3	<2	0.5	2.7	82.7	33.3
9	E-2	Common HE	Partial P4.1 deficiency	102.9	79.0	99.5	1.5	60.0	36.2	15.6	67	1.2	6.1	86.8	35.5
10	E-3	Common HE	Partial P4.1 deficiency	102.9	76.2	97.9	9.0	74.1	37.2	14.7	32	0.8	6.7	91.9	35.9
11	F	Common HE	Partial P4.1 deficiency	100.9	75.4	99.0	35.1	55.9	36.7	13.2	<2	0.5	8.3	86	35.1
12	G	Common HE	Partial P4.1 deficiency	99.8	82.2	110.6	33.3	61.7	40.3	10.7	<5	0.5	6	81	30.7

MCF cut-off value: 36.4; reference value: haptoglobin (19–170 mg/dL).