Gene Network Exploration of Crosstalk between Apoptosis and Autophagy in Chronic Myelogenous Leukemia

Table 1

List of selected genes, relevance, and supporting references.

HUGO gene symbol	Relevance	References
MCL1; BCL2; BAD	Apoptosis; autophagy; CML	[2, 19, 20]
BAX; BAK1	Apoptosis	[1–3, 6]
E2F1; E2F2; E2F3; MYC	Apoptosis; autophagy; cell cycle; CML	[3, 6, 19, 21, 22]
PIK3R2; PIK3R3; PIK3R5; AKT1; AKT2; AKT3	Apoptosis; cell cycle; CML	[19, 23–25]
ATG5; ATG7; ATG12; MAP1LC3B; BECN1	Autophagy	[2, 5, 6, 26]