Fully Automated Quantification of the Striatal Uptake Ratio of [^99mTc]-TRODAT with SPECT Imaging: Evaluation of the Diagnostic Performance in Parkinson’s Disease and the Temporal Regression of Striatal Tracer Uptake

Table 3

The ROC analysis for differentiating the PD patients from the nPD group and its subgroups based on the SRR calculated with our novel method that uses inversely transformed striatal and reference VOIs.

	Versus nPD group					Versus healthy controls					Versus essential tremor subjects
	Cutoff	Sensitivity	Specificity	Accuracy	AUC	Cutoff	Sensitivity	Specificity	Accuracy	AUC	Cutoff	Sensitivity	Specificity	Accuracy	AUC
PD group	1.73	92.1	90.2	91.8	0.94	1.76	93.2	96.4	93.4	0.98	1.67	87.7	84.8	87.4	0.91
Grou	1.73	88.1	90.2	88.8	0.91	1.76	90.7	96.4	91.8	0.97	1.73	88.1	81.8	86.8	0.87
Grou	1.73	89.0	90.2	89.4	0.93	1.75	90.0	96.4	91.4	0.97	1.73	90.0	81.8	88.0	0.90
Grou	1.66	94.3	91.8	93.2	0.96	1.72	97.7	100.0	98.3	0.99	1.66	94.3	84.8	91.7	0.93
Grou	1.51	93.3	95.1	94.2	0.97	1.68	96.7	100.0	97.7	0.98	1.47	91.7	97.0	93.5	0.97