Research Article
An Upgrade on the Rabbit Model of Anthracycline-Induced Cardiomyopathy: Shorter Protocol, Reduced Mortality, and Higher Incidence of Overt Dilated Cardiomyopathy
Figure 1
Echocardiograms in 2D and M-mode during induction of AICM. Echocardiograms in 2D parasternal long axis view (a, c, e) and M-mode of the left ventricle (LV) at the level of the papillary muscles (b, d, f). (a-b) Baseline, normal rabbit. (c-d) Rabbit with overt DCM. (e-f) Rabbit with CHF showing 4-chamber dilatation, pericardial effusion (PE), and severely reduced LV contractility. RV, right ventricle; LA, left atrium; RA, right atrium.
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