An Upgrade on the Rabbit Model of Anthracycline-Induced Cardiomyopathy: Shorter Protocol, Reduced Mortality, and Higher Incidence of Overt Dilated Cardiomyopathy

Figure 3

Changes in echocardiographic parameters and cTnI values during induction of AICM. (a) Left ventricular ejection fraction (LVEF). (b) Fractional shortening (FS). (c) Total circumferential shortening area (CSA). (d) Cardiac troponin I (cTnI) levels. Data expressed as mean ± SEM. Statistical significance is at ; (B), compared to basal; (C), compared to control; (), compared to DOX2; (), compared to DAU3; (), compared to DAU4.

(a)

(b)

(c)

(d)