Research Article
Cholesteryl Pullulan Encapsulated TNF-α Nanoparticles Are an Effective Mucosal Vaccine Adjuvant against Influenza Virus
Table 3
Antibody titer in blood plasma.
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The vaccine (IVV 0.3 µg/mouse) and adjuvant preparation (TNF/CHP nanoparticles 5 µg/mouse as TNF-α) were nasally administered to mice once a week up to 4 weeks. After that, 2 weeks of cessation period was set (4 + 2 weeks). Blood plasma was prepared and the anti-IVV IgG1 antibody was titrated (). n.d., not detected. |