Isotypes of Epstein-Barr Virus Antibodies in Rheumatoid Arthritis: Association with Rheumatoid Factors and Citrulline-Dependent Antibodies

Figure 4

Scattergrams showing individual levels of EAD IgG/IgM/IgA in plasma from RA patients divided into the two groups according to acute Methotrexate (MTX) treatment. EAD IgM/IgG/IgA levels divided into patients on MTX treatment and patients not on MTX treatment. RA patients on MTX (), RA patients not on MTX (), and RA patients total (). The two groups were compared using the Mann-Whitney test. Data are presented as mean ± SEM. Concentrations of antibodies are presented in arbitrary units. Statistical significant differences are indicated with , , , or for values less than 0.05, 0.01, 0.001, or 0.0001, respectively.