Localized and Sustained Delivery of Erythropoietin from PLGA Microspheres Promotes Functional Recovery and Nerve Regeneration in Peripheral Nerve Injury

<div>Histological and immunohistological analyses. (a) 8 weeks after surgery, the thinnest bands of scar tissue of H&amp;E staining of sciatic nerve tissues and more regular bundles were demonstrated in animals treated with PLGA/EPO compared with saline, PLGA, and EPO treatment. (b) Immunostaining against PGP 9.5 showed that immunopositive nerve fibers or deeper stained fibers were obviously more in PLGA/EPO treated animals.</div>

BioMed Research International

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Figure 3: Localized and Sustained Delivery of Erythropoietin from PLGA Microspheres Promotes Functional Recovery and Nerve Regeneration in Peripheral Nerve Injury 

Figure 3 | Localized and Sustained Delivery of Erythropoietin from PLGA Microspheres Promotes Functional Recovery and Nerve Regeneration in Peripheral Nerve Injury 