Key Proteins of Activating Cell Death Can Be Predicted through a Kainic Acid-Induced Excitotoxic Stress

Figure 8

Mascot search results for four significantly upregulated proteins in kainic acid-induced apoptosis based on probability based Mowse scores using the Mascot search engine. Possible proteins matched to the spectral masses with differential Mowse scores are shown as multiple bars on the -axis. Only proteins with Mowse scores greater than 64 (outside the shaded area) were considered statistically significantly different (). Proteins (without black arrow) were excluded if their masses corresponded to those for trypsin or keratins or to other irrelevant proteins. Black arrows indicate the Mowse score of 3-mercaptopyruvate sulfurtransferase, pyruvate dehydrogenase beta, tubulin beta 5, and heat shock protein 60 (HSP60).