Glycosylation-Based Serum Biomarkers for Cancer Diagnostics and Prognostics

Figure 2

Altered carbohydrate structures expressed in various cancers. (a) -linked oligosaccharides expressed on AFP in HCC patients, the majority of which have core fucosylation based on Johnson et al. [160]. (b) -linked oligosaccharide structures which change in abundance as the cancer progresses according to Saldova et al. [41]. (c) -linked oligosaccharide structures that are upregulated in lymph node metastasis positive breast cancers based on Pierce et al. [159]. (d) Tumour associated carbohydrate structures.