Clinical Study

Second Surgery in Insular Low-Grade Gliomas

Table 2

Summary of characteristics at tumor recurrence in the subgroup of patients who underwent a second surgery.

ParameterValue

Number of patients23
Sex
 Female8 (34.78%)
 Male15 (65.22%)
Mean age (yrs)42 (range 25–54)
Tumor side
 Left15 (65.22%)
 Right8 (34.78%)
Median time to tumor recurrence81 months (14–124)
Seizures relapse at second surgery11 (47.83%)
New contrast enhancement before second surgery11 (47.83%)
Intraoperative protocol
 Awake surgery16 (69.57%)
 General anesthesia7 (30.43%)
Immediate postoperative findings
 No deficits15 (65.22%)
 Neurological deficits08 (34.78%)
  Motor deficits4 (17.39%)
  Speech disorders3 (13.04%)
  Visual field disorders1 (4.35%)
Clinical outcome 6 months after surgery
 No deficits22 (95.65%)
 Neurological deficits1 (4.35%)
Histological data
 LGGs (WHO II)6 (26.09%)
 Anaplastic gliomas (WHO III)7 (30.43%)
 Glioblastomas (WHO IV)10 (43.48%)
 Mib1-Ki-67 expression16.5% (range 2–70%)