Identification of Subtype Specific miRNA-mRNA Functional Regulatory Modules in Matched miRNA-mRNA Expression Data: Multiple Myeloma as a Case

<div>miRNA-mRNA functional regulatory network of t(4;14) specific MFRM 1121-2 and functions of miRNAs and mRNAs. (a) Significant biological pathways that genes of MFRM 1121-2 identified by multiobjective GA participated in. 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(b) miRNA-mRNA functional regulatory network of t(4;14) specific MFRM 1121-2. There were 36 miRNAs, 382 mRNAs and 983 edges involved in the network. The miRNAs in red color were previously reported to play key roles in the pathogenesis of MM. (c) Significant biological pathways that genes of miRNA-mRNA functional regulatory network of t(4;14) specific MFRM 1121-2 participated in. 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BioMed Research International

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Figure 4

Figure 4: Identification of Subtype Specific miRNA-mRNA Functional Regulatory Modules in Matched miRNA-mRNA Expression Data: Multiple Myeloma as a Case 

Figure 4 | Identification of Subtype Specific miRNA-mRNA Functional Regulatory Modules in Matched miRNA-mRNA Expression Data: Multiple Myeloma as a Case 