Research Article

A Novel Method for the Synthesis of -Ofloxacin Kits Using D-Penicillamine as Coligand and Their Application as Infection Imaging Agent

Table 1

Effect of concentration of stannous chloride (reducing agent) and ofloxacin on the labeling efficiency (LE) of 99mTc-ofloxacin (%LE ± SD, ).

Reducing agentOfloxacin
Amount (g)Amount (mg)
2550 75 100 125 0.5 1 1.5 2.0 2.5

Labelling efficiency (%) 80.23 95.50 99.20 97.7 95.17 84.75 95.5 99.7 97.1 96.90
Free 99m17.4 3.57 0.40 1.7 2.0 13.54 0.25 0.15 1.1 1.0
Colloids/hydrolyzed (99mTcO2) 2.37 0.93 0.40 0.6 2.8 1.30 0.25 0.16 1.8 2.1