Proteomic Changes of Tissue-Tolerable Plasma Treated Airway Epithelial Cells and Their Relation to Wound Healing

Figure 5

Number of TTP-dose- and time-dependent up- and downregulated protein spots in S9 epithelial cells. (a) In the TTP-dose-dependent approach, protein spots of all TTP doses (30 s, 60 s, and 120 s) were compared with untreated samples (control) after each time point (24 h, 48 h, and 72 h). The number of significantly up- and downregulated protein spots (±1.5-fold, p ≤ 0.05) is shown. Note that a TTP-dose-dependent increase of the number of regulated protein spots could be observed for each time with the greatest effect after 24 h. (b) In the time-dependent approach, protein spots of each of 48 h and 72 h time points were compared to the corresponding 24 h time points. The number of significantly up- and downregulated protein spots (±1.5-fold, p ≤ 0.05) is shown.

(a)

(b)