Research Article

Hepatic and Splenic Acoustic Radiation Force Impulse Shear Wave Velocity Elastography in Children with Liver Disease Associated with Cystic Fibrosis

Table 4

Comparison between healthy patients and patients with CF with or without CFLD. ANOVA test and post hoc (Bonferroni) for SWV in right hepatic lobe (RHL), left hepatic lobe (LHL), and spleen. Student’s -test for the main variables, BMI and FEV1.

Group IGroup IIGroup IIIPost hoc comparison
Healthy childrenPatients with CF without liver diseasePatients with CFLD
Mean (SD)Mean (SD)Mean (SD)

RHL1.19 (0.13)1.18 (0.18)1.31 (0.16)6.0230.003Group I–group III
Group II-group III
LHL1.27 (0.19)1.27 (0.24)1.34 (0.30)0.9300.397
Spleen2.16 (0.35)2.51 (0.30)2.51 (0.31)18.154<0.0001Group I-group II
Group I–group III
FEV187.85 (15.21)91.05 (16.17) −0.7770.440
BMI17.67 (2.92)17.30 (3.19)0.480.633
GOT33.94 (13.03)64.17 (114.47)−1.820.073
GPT27.5 (14.08)54.13 (101.43)−1.790.077
GGT15.5 (14.56)79.79 (272.87)−1.640.106
AP187.89 (61.79)189.65 (73.82)−0.1050.917
TB0.63 (0.54)0.31 (0.16)1.2290.223
Glu93.79 (10.37)95.26 (16.75)−0.4540.651
Albu4.03 (0.30)3.97 (0.27)0.9430.349
Colin9370.23 (2051.30)8493.68 (1398.98)1.6930.096

RHL = right hepatic lobe; LHL = left hepatic lobe; FEV1 = pulmonary function; BMI = body mass index; GOT = aspartate-aminotransferase; GPT = alanine-aminotransferase; GGT = γ-glutamyl-transpeptidase; AP = alkaline phosphatase; TB = total bilirubin; Glu = glucose; Albu = albumin; Colin = cholinesterase.