Impact of Depression, Fatigue, and Global Measure of Cortical Volume on Cognitive Impairment in Multiple Sclerosis

Table 3

Backward linear regression: significant predictors of performance on each neuropsychological test.

Dependent variables	Predictors		Std	value	Adjusted
SRT-LTS	EDSS	−2.74	−0.30	0.03	0.19
SRT-CLTR	Dd; BDI-II	−0.67; −0.83	−0.26; −0.32	0.04; 0.01	0.20
SPART	BDI-II	−0.34	−0.39	<0.01	0.25
SDMT	EDSS; BDI-II	−4.55; −0.83	−0.44; −0.30	<0.01; <0.01	0.52
PASAT-3	BDI-II; NCV	−0.99; 0.11	−0.45; 0.25	<0.01; <0.01	0.37
PASAT-2	BDI-II; NCV	−0.72; 0.07	−0.43; 0.25	<0.01; 0.04	0.30
SRT-D	Age	−0.08	−0.32	0.01	0.09
SPART-D	BDI-II	−0.13	−0.32	0.01	0.09
WLG	NCV	−0.07	−0.41	0.03	0.09

, regression coefficient; Std , standardized regression coefficient; SRT-LTS, selective reminding test-long term storage; SRT-CLTR, selective reminding test-consistent long term retrieval; SPART, 10/36 spatial recall test; SDMT, symbol digit modalities test; PASAT, paced auditory serial addition test; SRT-D, delayed recall of the selective reminding test; SPART-D, delayed recall of the 10/36 spatial recall test; WLG, word list generation; EDSS, Expanded Disability Severity Scale; Dd, disease duration; BDI-II, Beck Depression Inventory-second edition; NCV, normalized cortical volume.