Functional Roles of Calreticulin in Cancer Biology

Table 1

Expression of CRT in different cancers.

Cancer	CRT levels^*	Clinical outcomes	Reference
Oral	Increased	—	[43]
Esophagus	Increased	survival (poor prognosis)	[44]
Breast	Increased	metastasis, invasion, survival	[45–47]
Pancreas	Increased	lymph node metastasis, UICC stage, survival	[48]
Gastric	Increased	lymph node metastasis, invasion, microvessel density, survival	[49]
Colon	Increased	—	[50]
Bladder	Increased	urinary CRT, histological grade, pathological T stage	[51–53]
Prostate	Increased	—	[54]
Vagina	Increased	—	[55]
^#Ovarian	Increased	Better response to chemotherapy	[55, 56]
^#Neuroblastoma	Increased	differentiation, survival	[57]

: increased; : decreased.
^*CRT levels in tumor tissue except ovarian carcinoma in effusion fluids.
^#Higher levels of CRT seem to correlate with good prognosis for the diseases.