Research Article

Effects of Dantrolene on Arrhythmogenicity in Isolated Regional Ischemia-Reperfusion Rabbit Hearts with or without Pacing-Induced Heart Failure

Figure 2

Dantrolene steepened APD80 restitution slopes in both groups. (a) Paired statistics for APD restitution (APDR) slopes. The data points (lines) are averages from each experiment. (b) representative examples of the spatial distribution of APDR curves at baseline (blue) and after dantrolene infusion (red) in both groups. The numbers under each subpanel are the maximum slopes of APD80 restitution at the selected evenly-spaced sites. DI: diastolic interval.
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