Modulation of the Cardiomyocyte Contraction inside a Hydrostatic Pressure Bioreactor: In Vitro Verification of the Frank-Starling Law

Figure 3

Contractility: the spheroidal syncytia showed minimum contractility at 200 mmHg (with statistically significant differences in comparison with the adjacent values at 100 and 300 mmHg []); the flat syncytia were characterized by maximum contractility at 100 mmHg (with statistically significant difference in comparison with the value at 0 mmHg [] and without statistically significant difference in comparison with the value at 200 mmHg []). Except at 200 mmHg, the contractility of spheroidal syncytia was significantly higher than the contractility of flat syncytia ().