Modulation of the Cardiomyocyte Contraction inside a Hydrostatic Pressure Bioreactor: In Vitro Verification of the Frank-Starling Law

Figure 6

Beat frequency: the spheroidal syncytia showed maximum beat frequency at 200 mmHg (with statistically significant differences in comparison with the adjacent values at 100 and 300 mmHg []); the flat syncytia were characterized by minimum beat frequency at 100 mmHg (with statistically significant differences in comparison with the adjacent values at 0 and 200 mmHg []). At all pressures, the beat frequency of spheroidal syncytia was significantly lower than the beat frequency of flat syncytia ().