Bone marrow concentrate and P-PRF either by mixing with a porcine collagen powder or by loading a esterified hyaluronic acid-derivative membrane; talar osteochondral lesions (mean size >1.5 cm2).
Improvement in AOFAS score from preoperatively to 12 months and from 12 to 36 months.
Bone marrow concentrate and P-PRF either by mixing with a porcine collagen powder or by loading a esterified hyaluronic acid-derivative membrane; talar osteochondral lesions (mean size 2 cm2).
Improvement in AOFAS score from preoperatively to 24 months, slight decrease at 36 and 48 months; inverse relationship at 24 months between the area of the lesion (< or >2 cm2) and the AOFAS score and at 48 months between the time from trauma to surgery and the AOFAS score.
Hyaluronic acid membrane filled with bone-marrow concentrate; a layer of P-PRF applied onto the implanted material; femoral condyle lesions ICRS III and IV.
Improvement at 29 months postoperatively in IKDC and KOOS scores.
PGA-HA scaffolds soaked by PRP to cover the defect site previously treated by microfracture procedure; femoral and tibial condyle cartilage lesions (size 1.5–5 cm2).
Improvement at 12 and 24 months postoperatively in KOOS scores.
y = years; PRP = Platelet-Rich Plasma; MSC = Mesenchymal Stem Cells; P-PRP = Pure PRP, with a low content of leukocyte; L-PRP = Leukocyte rich PRP; P-PRF = Pure Platelet-Rich Fibrin.