Research Article

Antioxidant and Proapoptotic Activities of Sclerocarya birrea [(A. Rich.) Hochst.] Methanolic Root Extract on the Hepatocellular Carcinoma Cell Line HepG2

Figure 4

Effect of MRE treatment on the morphology of HepG2 cell nuclei. Cells were treated with vehicle (a) and methanolic root extract at 10 (b), 50 (c), 100 (d), and 200 μg/mL for 24 h; cells were then stained with Hoechst 33258 and observed under a fluorescent microscope. Marked morphological changes (chromatin condensation and nuclear fragmentation) of cell apoptosis were clearly found.
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