Prokinetic Activity of Prunus persica (L.) Batsch Flowers Extract and Its Possible Mechanism of Action in Rats

Figure 5

EAE-induced histamine release from the rat colonic tissues. (a) Pretreatment of tissues of rat colon with EAE (10⁻⁶ g/mL) increased the concentration of histamine in the supernatant; pretreatment of the tissues with ketotifen (100 μM) prevented EAE-induced histamine release into the supernatant. (b) The histamine concentration in colon tissues treated with EAE was decreased; pretreatment of the colon tissues with ketotifen prevented the EAE-induced reduction in tissue histamine. Data are expressed as mean ± SEM () compared to the control groups.

(a)

(b)