Helicobacter pylori Outer Membrane Protein 18 (Hp1125) Is Involved in Persistent Colonization by Evading Interferon-γ Signaling

Figure 5

Δomp18 H. pylori infection increased cytokine and chemokine production. (a), (c), and (d) Analysis of MIP-2, IFN-γ, and IL-12 protein expressions in gastric tissues from C57BL/6 mice infected by H. pylori SS1 or Δomp18 H. pylori SS1 at week 8. (b) Analysis of IL-8 secretion from AGS cells infected by H. pylori 26695 or Δomp18 H. pylori 26695 with or without IFN-γ (50 pg/mL). Data are means ± SEM from 3 independent experiments. , , and .

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