Imbalance of the Nerve Growth Factor and Its Precursor as a Potential Biomarker for Diabetic Retinopathy

Figure 3

NGF decreases are consistent in vitreous and serum. Representative blots and statistical analysis of NGF protein expression are shown. NGF band intensities in vitreous and serum of diabetic (DB) and nondiabetic control (Con.) participants were normalized to Ponceau S and respective control group. (a) NGF expression is significantly reduced in diabetic vitreous, , compared to nondiabetic control group, ( = 4–10, ). (b) A significant decrease in NGF expression occurs in diabetic serum, , compared to nondiabetic controls ( = 6–11, ).

(a)

(b)