BioMed Research International / 2015 / Article / Tab 5 / Research Article
Survival of Mexican Children with Acute Lymphoblastic Leukaemia under Treatment with the Protocol from the Dana-Farber Cancer Institute 00-01 Table 5 Cox proportional-hazards model. Disease-free survival and death in paediatric patients with ALL who were younger than 16 years of age and who were treated at the paediatric haematology service of the specialist “La Raza” IMSS Medical Centre.
Characteristic DFS 3 years DFS 5 years Death 3 years Death 5 years RR 95% CI RR 95% CI RR
95% CI RR 95% CI Sex Male Female 1.202
0.839–1.721 0.316 1.137 0.811–1.595 0.457 1.307 0.861–1.984 0.208 1.413 0.956–2.088 0.082 Age (years) <1 4.288 0.531–34.611 0.172 3.947 0.495–31.454 0.195 0.000 0.000 0.000 3.616 0.446–29.352 0.229 1–5 1 1 1 1 5.1–9.99 1.504 0.942–2.403 0.087 1.384 0.891–2.148 0.148 1.556 0.887–2.728 0.123 4.573 0.940–2.633 0.085 >10 1.464 0.958–2.239 0.078 1.358 0.912–2.021 0.132 1.699 1.036–2.787 0.036 1.561 0.982–2.479 0.060 Leucocytes (1 × 109 /L) <10 10–20 1.302 0.792–2.140
0.297 1.489 0.942–2.354 0.089 1.437 0.821–2.516 0.205 1.495 0.876–2.550 0.140 20–50 1.193 0.655–2.175 0.564 1.253 0.712–2.205 0.435 1.286 0.650–2.545 0.470 1.322 0.688–2.541 0.402 50–100 1.133 0.520–2.470 0.753 1.167 0.556–2.449 0.683 0.990 0.390–2.510 0.982 1.374 0.620–3.044 0.434 >100 1.842 1.033–3.285 0.038 2.025 1.172–3.496 0.011 1.604 0.833–3.088 0.158 1.860 1.011–3.422 0.046 Phenotype B T 1.676 0.893–3.145 0.108 1.479 0.794–2.754 0.218 2.071 1.054–4.070 0.035 1.930 1.017–3.664 0.044 Risk Standard High 0.765 0.481–1.216 0.258 0.753 0.485–1.169 0.206 0.823 0.487–1.388 0.464 0.830 0.503–1.371 0.467
DFS: disease-free survival; RR: relative risk; CI: confidence interval.