Survival of Mexican Children with Acute Lymphoblastic Leukaemia under Treatment with the Protocol from the Dana-Farber Cancer Institute 00-01

Table 5

Cox proportional-hazards model. Disease-free survival and death in paediatric patients with ALL who were younger than 16 years of age and who were treated at the paediatric haematology service of the specialist “La Raza” IMSS Medical Centre.

Characteristic	DFS 3 years			DFS 5 years			Death 3 years			Death 5 years
	RR	95% CI		RR	95% CI		RR	95% CI		RR	95% CI
Sex
Male
Female	1.202	0.839–1.721	0.316	1.137	0.811–1.595	0.457	1.307	0.861–1.984	0.208	1.413	0.956–2.088	0.082
Age (years)
<1	4.288	0.531–34.611	0.172	3.947	0.495–31.454	0.195	0.000	0.000	0.000	3.616	0.446–29.352	0.229
1–5	1			1			1			1
5.1–9.99	1.504	0.942–2.403	0.087	1.384	0.891–2.148	0.148	1.556	0.887–2.728	0.123	4.573	0.940–2.633	0.085
>10	1.464	0.958–2.239	0.078	1.358	0.912–2.021	0.132	1.699	1.036–2.787	0.036	1.561	0.982–2.479	0.060
Leucocytes (1 × 10^9/L)
<10
10–20	1.302	0.792–2.140	0.297	1.489	0.942–2.354	0.089	1.437	0.821–2.516	0.205	1.495	0.876–2.550	0.140
20–50	1.193	0.655–2.175	0.564	1.253	0.712–2.205	0.435	1.286	0.650–2.545	0.470	1.322	0.688–2.541	0.402
50–100	1.133	0.520–2.470	0.753	1.167	0.556–2.449	0.683	0.990	0.390–2.510	0.982	1.374	0.620–3.044	0.434
>100	1.842	1.033–3.285	0.038	2.025	1.172–3.496	0.011	1.604	0.833–3.088	0.158	1.860	1.011–3.422	0.046
Phenotype
B
T	1.676	0.893–3.145	0.108	1.479	0.794–2.754	0.218	2.071	1.054–4.070	0.035	1.930	1.017–3.664	0.044
Risk
Standard
High	0.765	0.481–1.216	0.258	0.753	0.485–1.169	0.206	0.823	0.487–1.388	0.464	0.830	0.503–1.371	0.467

DFS: disease-free survival; RR: relative risk; CI: confidence interval.