Research Article

Prognostic Significance of the Tumor-Stroma Ratio in Epithelial Ovarian Cancer

Table 1

Clinicopathologic characteristics, demographics, and values for 838 EOC patients.

Age (years)Median: 55; range: 21–79
BMI (kg/m2)Median: 23; range: 15–47
Menopausal status
 Yes 505 (60.3%)
 No 333 (39.7%)
Histology
 Serous599 (71.5%)
 Mucous and others231 (28.5%)
Differentiation
420 (50.1%)
418 (49.9%)
FIGO stage (2009)
 I-II243 (29.0%)
 III-IV595 (71.0%)
With lymphadenectomy631 (75.2%)
 Pelvic527 (83.5%)
 Para-aortic + pelvic104 (16.5%)
Removed lymph nodesMedian: 25; range: 12–57
Lymph nodes metastasis
 No642 (76.6%)
 Yes196 (23.4%)
Residual disease
 <1 cm631 (75.3%)
 ≥1 cm207 (24.7%)
Ascites volume (mL)Median: 1000; range: 0–7000
 ≤1000591 (70.5%)
 >1000247 (29.5%)
Serum CA125 (U/mL)Median: 675; range: 23–7400
 ≤675521 (62.2%)
 >675317 (37.8%)
Tumor-stroma ratio (TSR)
 Stroma-poor (TSR < 50%)575 (68.6%)
 Stroma-rich (TSR ≥ 50%)263 (31.4%)