Research Article
Prognostic Significance of the Tumor-Stroma Ratio in Epithelial Ovarian Cancer
Table 3
Relationships between TSR and characteristics in 838 EOC patients.
| | Characteristics | Total | Stroma-poor | Stroma-rich | Stroma-rich proportion | | | () | () | () | () | | Number (%) | Number (%) | Number (%) | Number (%) |
| | Age, year | | | | | 0.365 | | ≤55 | 347 (41.41) | 232 (40.35) | 115 (43.73) | 115 (33.14) | | | >55 | 491 (58.59) | 343 (59.65) | 148 (56.27) | 148 (30.14) | | | Menopausal status | | | | | 0.820 | | Yes | 505 (60.26) | 348 (60.52) | 157 (59.70) | 157 (31.09) | | | No | 333 (39.74) | 227 (39.48) | 106 (40.30) | 106 (31.83) | | | Histology | | | | | 0.805 | | Serous | 599 (71.48) | 409 (71.13) | 190 (72.24) | 190 (31.72) | | | Mucous and others | 239 (28.52) | 166 (28.87) | 73 (27.76) | 73 (30.54) | | | Differentiation | | | | | 0.070 | | | 420 (50.12) | 276 (48.00) | 144 (54.75) | 144 (34.29) | | | | 418 (49.88) | 299 (52.00) | 119 (50.42) | 119 (28.47) | | | FIGO stage (2009) | | | | | <0.001 | | I-II | 243 (29.00) | 195 (33.91) | 48 (18.25) | 48 (19.75) | | | III-IV | 595 (71.00) | 380 (66.09) | 215 (81.75) | 215 (36.13) | | | Lymph nodes metastasis | | | | | <0.001 | | No | 657 (78.40) | 478 (83.13) | 179 (68.06) | 179 (27.25) | | | Yes | 181 (21.60) | 87 (16.87) | 94 (31.94) | 94 (51.93) | | | Residual disease | | | | | 0.796 | | <1 cm | 631 (75.30) | 431 (74.96) | 200 (76.05) | 200 (31.70) | | | ≥1 cm | 207 (24.70) | 144 (25.04) | 63 (23.95) | 63 (30.43) | | | Ascites volume (mL) | | | | | 0.464 | | ≤1000 | 591 (70.53) | 410 (71.30) | 181 (68.82) | 181 (30.63) | | | >1000 | 247 (29.47) | 165 (28.70) | 82 (31.18) | 82 (33.20) | | | Serum CA125 (U/mL) | | | | | 0.091 | | ≤675 | 521 (62.17) | 346 (60.17) | 175 (66.54) | 175 (33.59) | | | >675 | 317 (37.83) | 229 (39.83) | 88 (33.46) | 88 (27.76) | | | Recurrence | | | | | <0.001 | | No | 88 (10.50) | 82 (14.26) | 6 (2.28) | 6 (6.82) | | | Yes | 750 (89.50) | 493 (85.74) | 257 (97.72) | 257 (34.27) | |
|
|
