Influence of Acute Normobaric Hypoxia on Hemostasis in Volunteers with and without Acute Mountain Sickness
Table 2
Levels of aPTT, PT, platelet count, fibrinogen, SpO2, and heart rate.
ALL
AMS+
AMS−
Before
After
Before
After
Before
After
aPTT (26–37 sec)
37
31.5 ± 3.7
30.8 ± 3.4
0.091
23
30.9 ± 3.5
30.1 ± 3.0
0.100
14
32.5 ± 3.9
31.9 ± 3.7
0.489
PT (70–130%)
37
91.7 ± 10.3
94.3 ± 11.2
0.058
23
93.3 ± 8.8
93.7 ± 8.5
0.748
14
89.1 ± 12.3
95.2 ± 15.1
0.029
Platelet count (150–380 G/L)
37
226.0 ± 43.6
232.3 ± 61.4
0.340
23
233.5 ± 36.7
232.3 ± 64.1
0.908
14
213.8 ± 52.2
232.4 ± 58.9
0.000
Fibrinogen (210–400 mg/dL)
37
233.1 ± 36.9
238.6 ± 41.0
0.169
23
238.5 ± 38.8
246.2 ± 45.3
0.104
14
224.1 ± 33.0
226.2 ± 30.3
0.787
SpO2 (92–98%)
37
98.1 ± 1.2
85.1 ± 6.2
0.000
23
98.4 ± 1.0
85.3 ± 6.9
0.000
14
97.5 ± 1.5
84.1 ± 6.2
0.000
Heart rate (72–77 bpm)
37
76 ± 12
84 ± 15
0.008
23
79.8 ± 14.3
86.3 ± 16.4
0.011
14
72.6 ± 7.0
81.1 ± 12.0
0.042
aPTT, PT, platelet count, and plasma fibrinogen concentration for all participants (ALL) and for volunteers with (AMS+) and without (AMS−) AMS before and after hypoxia. Data are shown as mean values ± standard deviation. for as compared to pre exposure. Reference values are given in parentheses.