Influence of Acute Normobaric Hypoxia on Hemostasis in Volunteers with and without Acute Mountain Sickness

Table 3

Thrombin generation.

ALL

AMS+

AMS−

Before

After

Before

After

Before

After

ETP AUC (76–107%)

37

89.2 ± 10.3

89.9 ± 11.4

0.430

23

90.1 ± 11.0

90.8 ± 11.5

0.474

14

87.9 ± 9.4

88.3 ± 11.5

0.734

(79–110%)

37

94.0 ± 11.9

100.2 ± 16.7

0.019

23

95.4 ± 12.4

101.7 ± 17.1

0.083

14

91.7 ± 11.0

97.8 ± 16.5

0.122

(19.6–25.6 sec)

37

23.9 ± 4.9

23.3 ± 3.8

0.540

23

24.2 ± 5.9

23.8 ± 4.4

0.802

14

23.4 ± 2.4

22.5 ± 2.4

0.143

(50.8–72.0 sec)

37

66.5 ± 16.9

60.5 ± 7.7

n.a.

23

67.6 ± 18.2

59.7 ± 5.5

n.a.

14

64.7 ± 15.1

61.8 ± 9.8

0.465

n.a.: not applicable.
Endogenous thrombin potential (ETP AUC), maximum concentration of thrombin (), time to peak (), and lag-time () for all participants (ALL) and for volunteers with (AMS+) and without (AMS−) AMS before and after hypoxia. Data are shown as mean values ± standard deviation.
for as compared to pre exposure. Reference values are given in parentheses.