Clinical Study
Impact of Plasma Epstein-Barr Virus-DNA and Tumor Volume on Prognosis of Locally Advanced Nasopharyngeal Carcinoma
Table 1
Characteristics of 165 patients with locally advanced nasopharyngeal carcinoma.
| | Characteristics |
Pretreatment EBV-DNA
(cases/median copies/mL) | Tumor volume (medium, cm3) | | Negative (38) | Positive (127/9440) | GTVnx | GTVnd | Total |
| | Age (years) | | | | | | | <50 | 18 | 77/7210 | 73.6 | 29.7 | 106.3 | | ≥50 | 20 | 50/13850 | 69.3 | 24.6 | 108.6 | | Sex | | | | | | | Male | 30 | 92/9665 | 75.1 | 25.8 | 115.4 | | Female | 8 | 35/8620 | 68.1 | 26.2 | 102.8 | | UICC stage | | | | | | | III | 24 | 65/7590 | 64.8 | 24.5 | 87.9 | | IVa | 7 | 43/11400 | 108.4 | 17.1 | 136.8 | | IVb | 7 | 19/63400 | 70.4 | 53.4 | 144.1 | | T stage | | | | | | | T1 | 7 | 8/3945 | 47.0 | 24.7 | 62.3 | | T2 | 7 | 18/6265 | 51.0 | 29.3 | 83.5 | | T3 | 16 | 55/12000 | 67.9 | 27.4 | 104.7 | | T4 | 8 | 46/12650 | 113.7 | 20.2 | 142.3 | | N stage | | | | | | | N0-1 | 5 | 21/5520 | 76.3 | 14.5 | 92.3 | | N2 | 26 | 84/8855 | 71.8 | 25.3 | 103.6 | | N3 | 7 | 22/47700 | 65.0 | 58.8 | 138.0 |
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