Investigation of the Vitamin D Receptor Polymorphisms in Acromegaly Patients

Table 1

Demographic characteristics of acromegaly patients and control group.

	Acromegaly; ()	Control; ()
Gender (, %)
Female	31 (59.6)	53 (63.9)
Male	21 (40.4)	30 (36.1)
Age (y)	45.7 ± 1.9	43.1 ± 2.6
Age onset (y)	39.5 ± 1.9
Tumor size before treatment (, %)
Macroadenoma	36 (81.8)
Microadenoma	8 (18.2)
Number of resection (, %)
0	8 (17.8)
1	29 (64.4)
2	8 (17.8)
IGF1 (ng/mL)
Before treatment	882.5 ± 56
After treatment	234.6 ± 21.3
IGF1 (% ULN)
Before treatment	330.0 ± 21
After treatment	100.8 ± 10.4
GH (ng/mL)
Before treatment	18.3 ± 2.9
After treatment	1.3 ± 0.2
Remission status (, %)
Controlled	36 (80)
Uncontrolled	9 (20)
Tumor size after treatment (, %)
≥1 cm	10 (22.7)
<1 cm	34 (77.3)
25(OH)D3 (nmol/L)^*	5.5 ± 1.1	29.9 ± 2.1

Data are shown as mean ± standard error. IGF1 (%ULN): IGF1/upper limit of normal (age-matched) 100.
^*.