Fuchs Endothelial Corneal Dystrophy: Strong Association with rs613872 Not Paralleled by Changes in Corneal Endothelial TCF4 mRNA Level

Figure 1

Characteristic features of FECD. (a) Slit-lamp photography shows the presence of pathological guttae, focal excrescences of Descemet’s membrane at the level of corneal endothelium in a patient with FECD. (b) Confocal microscopy image of the corneal endothelium in a control subject demonstrates a regular mosaic of the endothelial monolayer with bright cell bodies and dark, hexagonal cell boundaries. (c) Confocal microscopy in a patient with FECD reveals pleomorphism and polymegathism of the endothelium and typical guttae as dark bodies with a central bright reflex.

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