Research Article
Fuchs Endothelial Corneal Dystrophy: Strong Association with rs613872 Not Paralleled by Changes in Corneal Endothelial TCF4 mRNA Level
Table 2
Genotype distribution and allele frequency of TCF4 rs613872 in patients with FECD and control subjects.
| | TCF4 rs613872 genotype | Genotype counts, (%) | OR dominant model (95% CI) | Allele counts, (%) |
statistic,
| | TT | TG | GG | Total | T | G |
| | FECD patients | 46 (18.25%) | 170 (67.46%) | 36 (14.29%) | 252 |
12.95
(8.63–19.42) | 262 (51.98%) | 242 (48.02%) |
<0.0001 | | Controls | 240 (74.30%) | 74 (22.91%) | 9 (2.79%) | 323 | 554 (85.76%) | 92 (14.24%) |
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