Substance P Receptor Antagonism: A Potential Novel Treatment Option for Viral-Myocarditis

Figure 1

Effect of aprepitant or fasudil treatment on mortality rates in EMCV-infected mice. Effect of (a) aprepitant or (b) fasudil treatment on EMCV-induced mortality. Percent survival rate was determined in EMCV-infected mice with and without aprepitant or fasudil treatment over 14 days following infection (infected, with versus without aprepitant pretreatment, or infected, with versus without aprepitant posttreatment (both , Kaplan-Meier analysis), infected, with versus without fasudil pre- or posttreatment (both , Kaplan-Meier analysis) ()).

(a)

(b)