The Role of Omega-3 Polyunsaturated Fatty Acids in the Treatment of Patients with Acute Respiratory Distress Syndrome: A Clinical Review

Table 1

Berlin definition of ARDS.

Timing	Within one week of a known clinical insult or new or worsening respiratory symptoms.
Chest imaging	Bilateral opacities not fully explained by effusions, lobar/lung collapse, or nodules.
Origin of oedema	Respiratory failure not fully explained by cardiac failure or fluid overload. Need for objective assessment (e.g., echocardiography) to exclude hydrostatic oedema if no risk factors are present.
Oxygenation
Mild	200 mmHg < PaO2/FIO2 ≤ 300 mmHg with PEEP or CPAP ≥ 5 cmH2O
Moderate	100 mmHg < PaO2/FIO2 ≤ 200 mmHg with PEEP ≥ 5 cmH2O
Severe	PaO2/FIO2 ≤ 100 mmHg with PEEP ≥ 5 cmH2O

P_aO₂: partial pressure of arterial oxygen; F_IO₂: fraction of inspired oxygen; PEEP: positive end expiratory pressure; CPAP: continuous positive airway pressure.