Review Article

Endoscopic Sphincterotomy with Large Balloon Dilation versus Endoscopic Sphincterotomy for Bile Duct Stones: A Systematic Review and Meta-Analysis

Table 1

Baseline characteristics comparing endoscopic sphincterotomy with large balloon dilation (EPLBD) versus endoscopic sphincterotomy (EST).

TrialsSiteNumber of patients Stone size (diameter, mm)EPLBD procedure The length of the sphincterotomy
EPLBDESTRangeMeanBalloon size (mm)balloon inflated timeEPLBDEST

Heo et al., 2007 [12]Korea100100≤4016.0 ± 0.7 (EPLBD) versus15.0 ± 0.7 (EST)12–2060 seconds Limited to a third size of full lengthComplete sphincterotomy
Kim et al., 2009 [13]Korea272815–5020.8 ± 4.1 (EPLBD) versus 20.5 ± 5.7 (EST)15, 16.5, and 18Not mentionedMidportion of the papillaComplete sphincterotomy
Teoh et al., 2013 [14]Hong Kong 7378Not mentioned12.47 (5–35) (EPLBD) versus 13.26 (5–40) (EST)13–1530 seconds One-third to one-half of the papillaComplete sphincterotomy
Stefanidis et al., 2011 [15]Greece454512–20Not mentioned15, 18, and 2010–20 secondsComplete sphincterotomyComplete sphincterotomy