Research Article
Genetic Variations in Inflammatory Response Genes and Their Association with the Risk of Prostate Cancer
Table 3
Association between polymorphisms and prostate cancer risk.
| | Genotype | Case () | Control () | OR (95% CI) | |
| | NFKB1 -94 ins/del | | | | | | Ins/Ins | 198 | 212 | Ref. | — | | Ins/Del | 246 | 355 | 0.74 (0.58 to 0.96) | 0.02 | | Del/Del | 99 | 186 | 0.57 (0.42 to 0.78) | <0.01 | | NFKBIA -826C/T | | | | | | CC | 382 | 541 | Ref. | — | | CT | 152 | 198 | 1.09 (0.85 to 1.39) | 0.51 | | TT | 9 | 14 | 0.91 (0.39 to 2.13) | 0.83 | | COX-2 (-1195G>A) | | | | | | GG | 71 | 158 | Ref. | — | | GA | 269 | 378 | 1.58 (1.15 to 2.18) | 0.01 | | AA | 203 | 217 | 2.08 (1.48 to 2.92) | <0.01 | | COX-1 (50C>T) | | | | | | CC | 452 | 655 | Ref. | — | | CT | 83 | 92 | 1.31 (0.95 to 1.80) | 0.10 | | TT | 8 | 6 | 1.93 (0.67 to 5.61) | 0.23 | | PPARG Pro12Ala | | | | | | Pro/pro | 483 | 676 | Ref. | — | | Pro/ala | 57 | 73 | 1.09 (0.76 to 1.58) | 0.63 | | Ala/ala | 3 | 4 | 1.05 (0.23 to 4.71) | 0.95 |
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