A New Mechanism of Vitamin C Effects on A/FM/1/47(H1N1) Virus-Induced Pneumonia in Restraint-Stressed Mice

Figure 6

The effect of vitamin C on mRNA expression of CYP11B, CYP11A, and CYP21A in restraint-stressed mice after infection. The CYP11B, CYP11A, and CYP21A mRNA expression in adrenal tissues from mice were determined by RT-PCR and normalized by 18S. N, normal; Res, restraint; R, ribavirin; E, edaravone; Vc-L, vitamin C-low dosage; Vc-H, vitamin C-high dosage. Significant difference from the normal group at , and from the restraint-stressed group at , .