Research Article

CD40 Ligand Deficient C57BL/6 Mouse Is a Potential Surrogate Model of Human X-Linked Hyper IgM (X-HIGM) Syndrome for Characterizing Immune Responses against Pathogens

Table 1

Serum dilutions to determine basal immunoglobulin concentrations.

ImmunoglobulinSerum dilutions
WTC57-CD40L

IgA1 : 500 and 1 : 10001 : 250 and 1 : 500
IgM and total IgG1 : 4000 and 1 : 80001 : 4000 and 1 : 8000
IgG11 : 1000 and 1 : 20001 : 250 and 1 : 500
IgG2c1 : 250 and 1 : 5001 : 250 and 1 : 500
IgG2b1 : 2000 and 1 : 40001 : 1000 and 1 : 2000
IgG31 : 1500 and 1 : 30001 : 1500 and 1 : 3000

WT = wild type mice.