Osteoarticular Expression of Musashi-1 in an Experimental Model of Arthritis
Table 1
Comparative study of morphological variables in DBA1/J mice after 21 and 28 days of starting treatment.
Variables
Control group
Etanercept group*
values
Control group
Etanercept group*
values
Day 46 after immunization
Day 53 after immunization
Number of joints
2.1 ± 0.69
1.8 ± 0.88
0.412
2.45 ± 1.01
1.9 ± 0.56
0.006
Pannus
1 ± 0.21
0.9 ± 0.35
0.449
0.7 ± 0.31
1 ± 0
0.467
B & C injury
1.8 ± 0.71
1.3 ± 0.78
0.278
2 ± 0.94
1.55 ± 0.68
0.045
Inflammation
1.5 ± 1
1.3 ± 1
0.661
1.55 ± 0.83
1.1 ± 0.69
0.036
Bone marrow
0.6 ± 0.47
0.5 ± 0.39
0.613
0.55 ± 0.42
0.55 ± 0.43
0.930
Soft tissue
0.15 ± 0.15
0.2 ± 0.21
0.557
0.35 ± 0.31
0.15 ± 0.15
0.010
Mean score
6.85 ± 2.95
5.8 ± 3.37
0.469
8 ± 3.55
6 ± 2.12
0.011
Values are expressed as mean ± standard deviation; *treatment: etanercept 2 mg/week; B & C: bone and cartilage; Student’s -test. See Figure 3 for details.
