Research Article
Brain Parenchymal Fraction: A Relatively Simple MRI Measure to Clinically Distinguish ALS Phenotypes
Table 3
Clinical characteristics of ALS patients with FTD.
| Patient | Gender | Age (yr) | Site of onset | Features of FTD | Extent | Domain affected | (at time of MRI) |
| 1 | F | 67 | Speech | Mild | bv., ex., l. | 2 | F | 75 | UE | Mild | ex., l. | 3 | F | 60 | Speech | Mod. | bv., ex. | 4 | F | 58 | Speech | Mod. | bv., l. | 5 | F | 60 | Cognitive | Mod. | bv. | 6 | M | 63 | Speech | Severe | bv., l. (PNFA) | 7 | M | 75 | Cognitive | Severe | bv., mem. | 8 | F | 53 | Speech | Severe | bv., l. | 9 | F | 52 | Speech | Severe | g. | 10 | M | 59 | Cognitive | Severe | g. | 11 | M | 87 | UE, LE | Severe | g. | 12 | F | 69 | Cognitive | Severe | bv., l. | 13 | F | 68 | Cognitive | Severe | bv., ex. | 14 | F | 67 | LE | Severe | ex., l. (sem.), mem. | 15 | F | 65 | Cognitive | Severe | bv., l. | 16 | F | 63 | LE | Severe | bv., ex., l. | 17 | F | 77 | Speech | Severe | bv., ex., l. | 18 | M | 78 | LE | Severe | g. |
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bv. = behavior; Cog. = cognitive; ex. = executive; g. = global (bv. + ex. + l. + mem. present); l. = language; LE = lower extremity; mem. = memory; PNFA = progressive nonfluent aphasia; sem. = semantic; and UE = upper extremity.
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