Preoperative RAS Mutational Analysis Is of Great Value in Predicting Follicular Variant of Papillary Thyroid Carcinoma

Table 6

The subtypes of BRAF and RAS gene mutations in 104 FNA samples of atypia of undetermined significance or follicular lesion of undetermined significance.

Nucleotide change	Amino acid change	Number of mutated cases
BRAF codon 600
c.1799T>A	p.V600E	51
BRAF codon 601
c.1801A>G	p.K601E	6
NRAS codon 12
c.34G>A	p.G12S	1
NRAS codon 61
c.182A>G	p.Q61R	29
c.181C>A	p.Q61K	7
HRAS codon 61
c.182A>G	p.Q61R	4
c.181C>A	p.Q61K	3
KRAS codon 61
c.182A>G	p.Q61R	2
c.180_181TC>AA	p.Q61K	1