Research Article

Salivary Desmoglein Enzyme-Linked Immunosorbent Assay for Diagnosis of Pemphigus Vulgaris: A Noninvasive Alternative Test to Serum Assessment

Table 3

The values of salivary and serum anti-Dsg 1 and anti-3 ELISA in PV patients regarding their phenotype and controls.

Disease phenotypeSalivary ELISASerum ELISA
Anti-Dsg1*Anti-Dsg3*Anti-Dsg1*Anti-Dsg3*
Median (IQR**)Median (IQR)Median (IQR)Median (IQR)

Mucosal1.80 (1.3–6.9)21 (8.3–92)3.2 (2.3–28)163 (40–322)
Cutaneous2.40 (1.75–80.4)3.8 (1.6–14.8)186 (94.15–376.5)165 (32.15–358.5)
Mucocutaneous17.35 (2.15–114.25)182 (35.75–255)136 (58.5–241.75)310 (244.5–399.25)
Overall8.4 (1.7–75.25)102.5 (16.925–215.25)90 (12.225–213.25)297 (200.25–382)
Controls2 (1.6–3.1)2.1 (1.4–4.8)1.5 (1.1–1.9)1.2 (1.1–1.6)

*The unit for measurement is RU/mL.
**Interquartile range.