High LIN28A Expressing Ovarian Cancer Cells Secrete Exosomes That Induce Invasion and Migration in HEK293 Cells

Figure 9

Detection of LIN28A and LIN28B protein in exosomes. Western blot was used to determine the presence of LIN28A protein in exosomes (columns 3–5). The cytoplasmic/mitochondrial protein cytochrome C (CYTO C) was used as a negative control to exclude nonexosomal fractions, and tumor susceptibility gene 101 (TSG101), a component of the endosomal sorting, and EPCAM (epithelial cell adhesion molecule) are used as positive controls for exosomes.