Levels of Anti-HBs Antibody in HBV-Vaccinated Students Enrolled in the Faculty of Medicine, Dentistry and Health Professions of a Large Italian University
Table 1
Univariate and multivariate analysis of level of anti-HBsAg antibodies according to sociodemographic factors, number of doses of HBV vaccination, academic year, and type of biomedical students.
Titers (mIU/mL) (%)
Crude OR (95% CI)
Adjusted OR (95% CI)
0–9
10–1121.63
>1121.64
Gender
Males
54 (50.9)
46 (43.4)
6 (5.7)
0.998
1
1
Females
132 (50.6)
114 (43.7)
15 (5.7)
1.01 (0.65–1.59)
1.11 (0.69–1.78)
Age group dose 1
1–10 years
24 (31.2)
46 (59.7)
7 (9.1)
0.003
2.70 (1.51–4.76)
2.44 (1.41–4.35)
11–17 years
107 (53.0)
87 (43.1)
8 (4.0)
1
1
Age group
≤20
88 (56.4)
59 (37.8)
9 (5.8)
0.010
1**
1**
21–24
39 (37.1)
61 (58.1)
5 (4.8)
≥25
48 (55.2)
32 (36.8)
7 (8.0)
0.77 (0.47–1.25)
1.17 (0.67–2.04)
Number of doses
1
22 (78.6)
5 (17.9)
1 (3.6)
0.001*
1
1
2
20 (71.4)
8 (28.6)
0 (0.0)
1.47 (0.43–4.96)
1.4 (0.40–4.86)
3
129 (46.4)
134 (48.2)
15 (5.4)
(1.7 – 10.91)
(1.44–10.57)
4
15 (42.9)
15 (42.9)
5 (14.3)
Academic year
2003-2004
2 (100.0)
0 (0.0)
0 (0.0)
0.001*
2004-2005
2 (66.7)
1 (33.3)
0 (0.0)
2005-2006
30 (78.9)
8 (21.1)
0 (0.0)
2006-2007
140 (61.9)
78 (34.5)
8 (3.5)
1
1
2007-2008
6 (16.7)
26 (72.2)
4 (11.1)
17.69° (8.5–36.97)
17.0° (8.23–35.2)
2008-2009
2 (10.6)
14 (73.7)
3 (15.7)
2009-2010
4 (8.9)
35 (77.8)
6 (13.3)
Type of students
Health Professions
182 (50.6)
158 (43.9)
20 (5.6)
0.763
1
1
Medicine
4 (44.4)
4 (44.4)
1 (11.2)
0.93 (0.47–1.86)
0.85 (0.46–1.89)
Yates correction; **the reference group is age ≤24 years; the OR is related to 3-4 doses versus 1 dose; °the OR is related to 2007 and over versus before 2007.
